Dong Quai
Also known as: angelica sinensis, female ginseng, dang gui, tang kuei
Recommended Dosage
500–1500 mg
Traditional Chinese Medicine herb for menstrual and menopausal support, almost always used in combination formulas. Weak evidence as a standalone supplement. Significant blood-thinning properties via coumarins. Photosensitizing. Better studied herbs exist for similar goals.
Quick Facts
Evidence
Grade C
Studies
1
Interactions
2
Forms
1
Evidence Rating: Grade C — Preliminary
Limited human trials, mostly animal or in-vitro data. Promising but not yet proven in robust human studies.
Interaction Warnings
Contains coumarins with significant anticoagulant properties — increases bleeding risk substantially.
May have weak estrogenic effects — avoid in hormone-sensitive conditions.
Important Notes
- Traditionally used in TCM formulas for menstrual support — rarely used alone in traditional practice
- Contains photosensitizing compounds (furanocoumarins) — increased sunburn risk
- Strong anticoagulant properties — stop before surgery
- Not recommended during pregnancy (may stimulate uterine contractions)
- Evidence as a standalone supplement is weak — most TCM use is in multi-herb combinations
Clinical Evidence (1 study)
Dong quai (Angelica sinensis) for menopausal symptoms: a systematic review
Lau CBS et al. (2005) — Menopause
Limited evidence as a standalone herb for menopausal symptoms; traditionally used in multi-herb TCM formulas rather than alone
Alternatives to Consider
These supplements target similar goals and may be worth considering alongside or instead of Dong Quai.
Vitex (Chasteberry)
Grade BWell-studied herbal remedy for PMS symptoms, particularly mood changes, breast tenderness, and irritability. Works by modulating dopamine and reducing prolactin. Evidence is solid for PMS but takes 2-3 cycles. Avoid with hormonal medications.
Black Cohosh
Grade CTraditional herbal remedy primarily used for menopausal symptoms including hot flashes and mood disturbances. Moderate evidence of efficacy. Rare but serious liver toxicity reports warrant caution. Avoid in hormone-sensitive conditions.
Evening Primrose Oil
Grade CRich source of gamma-linolenic acid (GLA), an anti-inflammatory omega-6 fatty acid. Used for skin conditions, PMS, and inflammation. Evidence is moderate. Takes weeks to show effects. Avoid with seizure medications.
Related Supplements
Black Cohosh
Grade C — PreliminaryTraditional herbal remedy primarily used for menopausal symptoms including hot flashes and mood disturbances. Moderate evidence of efficacy. Rare but serious liver toxicity reports warrant caution. Avoid in hormone-sensitive conditions.
Vitex (Chasteberry)
Grade B — Moderate EvidenceWell-studied herbal remedy for PMS symptoms, particularly mood changes, breast tenderness, and irritability. Works by modulating dopamine and reducing prolactin. Evidence is solid for PMS but takes 2-3 cycles. Avoid with hormonal medications.
Evening Primrose Oil
Grade C — PreliminaryRich source of gamma-linolenic acid (GLA), an anti-inflammatory omega-6 fatty acid. Used for skin conditions, PMS, and inflammation. Evidence is moderate. Takes weeks to show effects. Avoid with seizure medications.
Magnesium Glycinate
Grade A — Strong EvidenceHighly bioavailable form of magnesium. Strong evidence for sleep quality, muscle relaxation, and stress reduction. Most adults are deficient.
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⚕️ Important Disclaimer
This information is for educational purposes only. It is not medical advice. Always consult a healthcare provider before starting any supplement regimen, especially if you take medications or have health conditions.
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