Astragalus
Also known as: astragalus membranaceus, huang qi, astragalus root
Recommended Dosage
500–2000 mg
Foundational Traditional Chinese Medicine herb with immune-modulating and potential anti-aging properties. Astragalus polysaccharides support immune function, and cycloastragenol may activate telomerase. Mostly preclinical evidence but long traditional use. Avoid with immunosuppressants.
Quick Facts
Evidence
Grade C
Studies
1
Interactions
2
Forms
1
Evidence Rating: Grade C — Preliminary
Limited human trials, mostly animal or in-vitro data. Promising but not yet proven in robust human studies.
Interaction Warnings
Immune-stimulating properties may counteract immunosuppressive therapy.
May have diuretic effects — could affect lithium levels.
Important Notes
- One of the most important herbs in Traditional Chinese Medicine (TCM)
- Active compounds include astragalosides and polysaccharides
- Telomerase activation (TA-65) is derived from astragalus — longevity interest
- Avoid in autoimmune conditions due to immune stimulation
- Quality and species authentication matter — adulteration is common
Clinical Evidence (1 study)
Astragalus membranaceus: a review of its immunomodulatory and anti-aging properties
Liu P et al. (2017) — Am J Chin Med
Astragalus polysaccharides enhance immune cell activity, support telomerase activation, and demonstrate anti-aging potential in preclinical studies
View on PubMedAlternatives to Consider
These supplements target similar goals and may be worth considering alongside or instead of Astragalus.
Quercetin
Grade BVersatile flavonoid with senolytic, immune, and anti-inflammatory properties. Zinc ionophore. Phytosome form critical for absorption.
Spirulina
Grade BNutrient-dense cyanobacterium with strong evidence for immune support, lipid improvement, and antioxidant protection. Complete protein source. Quality sourcing is critical to avoid contamination.
Turkey Tail Mushroom
Grade BMost-studied medicinal mushroom for immune support. PSK/PSP polysaccharides are approved as anticancer adjunct therapy in Japan. Strong evidence for immune modulation and gut microbiome support.
Related Supplements
Quercetin
Grade B — Moderate EvidenceVersatile flavonoid with senolytic, immune, and anti-inflammatory properties. Zinc ionophore. Phytosome form critical for absorption.
Spirulina
Grade B — Moderate EvidenceNutrient-dense cyanobacterium with strong evidence for immune support, lipid improvement, and antioxidant protection. Complete protein source. Quality sourcing is critical to avoid contamination.
Chlorella
Grade C — PreliminaryGreen algae rich in chlorophyll, protein, iron, and B12. Evidence for immune support and metabolic markers. Broken-cell wall form required for bioavailability. Complementary to spirulina.
Turkey Tail Mushroom
Grade B — Moderate EvidenceMost-studied medicinal mushroom for immune support. PSK/PSP polysaccharides are approved as anticancer adjunct therapy in Japan. Strong evidence for immune modulation and gut microbiome support.
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⚕️ Important Disclaimer
This information is for educational purposes only. It is not medical advice. Always consult a healthcare provider before starting any supplement regimen, especially if you take medications or have health conditions.
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